The cortex and hippocampus are two key brain areas that play critical roles in normal functions such as learning and memory as well as disorders such as epilepsy. Prof Mala Shah's research interests lie in understanding how neurons within these brain areas process information under physiological conditions and during epileptogenesis. Her group is particularly interested in determining how voltage-gated ion channels regulate neuronal intrinsic excitability and synaptic transmission in cortical and hippocampal neurons. Specific projects include: (1) HCN channels and epileptogenesis, (2) presynaptic HCN channels, calcium channels, and neuronal excitability, (3) function and regulation of axonal Kv7 channels.
Host: Prof Annette Dolphin